Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
| Characterization of flounder (Paralichthys olivaceus) FoxD5 and its function in regulating myogenic regulatory factor | |
Tan Xungang1 ; Zhang Yuqing1,2; Sun Wei1,2; Zhang Peijun1; Xu Yongli1; Tan, XG (reprint author), Chinese Acad Sci, Inst Oceanol, EMBLC, Qingdao 266071, Peoples R China.
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| 2012-03-01 | |
| 发表期刊 | CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY
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| ISSN | 0254-4059 |
| 卷号 | 30期号:2页码:286-294 |
| 文章类型 | Article |
| 摘要 | As one member of winged helix domain transcription factors, FoxD5 was reported to be a trunk organizer. Recent study showed that zebrafish foxd5 is expressed in the somites. To further understand the function of FoxD5 in fish muscle development, the FoxD5 gene was isolated from flounder. Its expression pattern was analyzed by in situ hybridization, while its function in regulating myogenic regulatory factor, MyoD, was analyzed by ectopic expression. It showed that flounder FoxD5 was firstly expressed in the tailbud, adaxial cells, and neural plate of the head. In flounder embryo, FoxD5 is expressed not only in forebrain but also in somite cells that will form muscle in the future. When flounder FoxD5 was over-expressed in zebrafish by microinjection, the expression of zebrafish MyoD in the somites was reduced, suggesting that FoxD5 is involved in myogenesis by regulating the expression of MyoD. |
| 关键词 | Flounder Foxd5 Muscle Over-expression In Situ Hybridization Myogenic Regulatory Factor |
| 学科领域 | Limnology ; Oceanography |
| DOI | 10.1007/s00343-012-1080-4 |
| URL | 查看原文 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000301001900013 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/12297 |
| 专题 | 实验海洋生物学重点实验室 |
| 通讯作者 | Tan, XG (reprint author), Chinese Acad Sci, Inst Oceanol, EMBLC, Qingdao 266071, Peoples R China. |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, EMBLC, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 第一作者单位 | 中国科学院海洋研究所 |
| 推荐引用方式 GB/T 7714 | Tan Xungang,Zhang Yuqing,Sun Wei,et al. Characterization of flounder (Paralichthys olivaceus) FoxD5 and its function in regulating myogenic regulatory factor[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2012,30(2):286-294. |
| APA | Tan Xungang,Zhang Yuqing,Sun Wei,Zhang Peijun,Xu Yongli,&Tan, XG .(2012).Characterization of flounder (Paralichthys olivaceus) FoxD5 and its function in regulating myogenic regulatory factor.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,30(2),286-294. |
| MLA | Tan Xungang,et al."Characterization of flounder (Paralichthys olivaceus) FoxD5 and its function in regulating myogenic regulatory factor".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 30.2(2012):286-294. |
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