Flounder (Paralichthys olivaceus) FoxD1 and its regulation on the expression of myogenic regulatory factor, MyoD

doi:10.2478/s11756-012-0096-8

IOCAS-IR > 实验海洋生物学重点实验室

	Flounder (Paralichthys olivaceus) FoxD1 and its regulation on the expression of myogenic regulatory factor, MyoD
	Zhang, Yuqing 1,2; Tan, Xungang1 ; Sun, Wei 1,2; Zhang, Pei-Jun 1; Tan, XG (reprint author), Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China.
	2012-10-01
发表期刊	BIOLOGIA
ISSN	0006-3088
卷号	67 期号:5 页码:992-1000
文章类型	Article
摘要	It has been reported that FoxD1 plays important roles in formation of several different tissues, such as retina and kidney in vertebrates. The function of FoxD1 in muscle development is, however, unclear although it is expressed in muscle cells in zebrafish. Muscles are the major tissue in fish, which serves as a rich protein source in our diet. To further understand the function of FoxD1 in fish muscle development, here we isolated and characterized the FoxD1 gene from flounder (Paralichthys olivaceus), a valuable sea food and an important fish species in aquaculture in Asia. We analyzed its expression pattern and function in regulating myogenic regulatory factor, MyoD, one of the earliest marker of myogenic commitment. In situ hybridization revealed that FoxD1 was expressed in the tailbud, adaxial cells, posterior intestine, forebrain, midbrain and half of the retina in flounder embryos. Functional studies demonstrated that when flounder FoxD1 was over-expressed in zebrafish by microinjection, MyoD expression was decreased, suggesting that FoxD1 may be involved in myogenesis by regulating the expression of MyoD.
关键词	Flounder Foxd1 Protein Over-expression Muscle Development
学科领域	Biology
DOI	10.2478/s11756-012-0096-8
URL	查看原文
收录类别	SCI
语种	英语
WOS记录号	WOS:000307767300022
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/12330
专题	实验海洋生物学重点实验室
通讯作者	Tan, XG (reprint author), Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China.
作者单位	1.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China
第一作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Zhang, Yuqing,Tan, Xungang,Sun, Wei,et al. Flounder (Paralichthys olivaceus) FoxD1 and its regulation on the expression of myogenic regulatory factor, MyoD[J]. BIOLOGIA,2012,67(5):992-1000.
APA	Zhang, Yuqing,Tan, Xungang,Sun, Wei,Zhang, Pei-Jun,&Tan, XG .(2012).Flounder (Paralichthys olivaceus) FoxD1 and its regulation on the expression of myogenic regulatory factor, MyoD.BIOLOGIA,67(5),992-1000.
MLA	Zhang, Yuqing,et al."Flounder (Paralichthys olivaceus) FoxD1 and its regulation on the expression of myogenic regulatory factor, MyoD".BIOLOGIA 67.5(2012):992-1000.

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