Talascortenes A-G, Highly Oxygenated Diterpenoid Acids from the Sea-Anemone-Derived Endozoic Fungus Talaromyces scorteus AS-242

doi:10.1021/acs.jnatprod.0c00628

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	Talascortenes A-G, Highly Oxygenated Diterpenoid Acids from the Sea-Anemone-Derived Endozoic Fungus Talaromyces scorteus AS-242
	Meng, Ling-Hong1,2 ; Li, Xiao-Ming 1,2; Zhang, Fan-Zhong1,3 ; Wang, Ya-Nan 1,3; Wang, Bin-Gui1,2
	2020-08-28
发表期刊	JOURNAL OF NATURAL PRODUCTS
ISSN	0163-3864
卷号	83 期号:8 页码:2528-2536
通讯作者	Meng, Ling-Hong(menglh@ms.qdio.ac.cn) ; Wang, Bin-Gui(wangbg@ms.qdio.ac.cn)
摘要	Eight new diterpenoid acids, namely, talascortenes A-G (1-7) and 5 alpha,9 beta-dihydroxyisocupressic acid (8), with four different carbon skeletons, were isolated and identified from the endozoic fungal strain Talaromyces scorteus AS-242 that was obtained from the inner fresh tissue of a deep sea Cerianthus sp. sea anemone. The structures of the new compounds were elucidated by detailed interpretation of NMR and mass spectrometric data. X-ray crystallographic analysis of compounds 1-5 and 7 confirmed their structures and absolute configurations. Compounds 1-8 showed inhibitory activities against several human, aquatic, and plant pathogens with MIC values ranging from 1 to 32 mu g/mL.
DOI	10.1021/acs.jnatprod.0c00628
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[41976090] ; Qingdao National Laboratory for Marine Science and Technology[YQ2018NO08] ; Qingdao Science and Technology Bureau[18-2-2-59-jch] ; Youth Innovation Promotion Association of the Chinese Academy of Sciences[2017250] ; Research Vessel KEXUE of the National Major Science and Technology Infrastructure from the Chinese Academy of Sciences[KEXUE2018G28] ; Taishan Scholar Project from Shandong Province[ts201511060]
WOS研究方向	Plant Sciences ; Pharmacology & Pharmacy
WOS类目	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号	WOS:000566765000024
出版者	AMER CHEMICAL SOC
引用统计	被引频次：30[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/168747
专题	实验海洋生物学重点实验室
通讯作者	Meng, Ling-Hong; Wang, Bin-Gui
作者单位	1.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Scicncc & Technol, Lab Marine Biol & Biotechnol, Qingdao 266237, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Meng, Ling-Hong,Li, Xiao-Ming,Zhang, Fan-Zhong,et al. Talascortenes A-G, Highly Oxygenated Diterpenoid Acids from the Sea-Anemone-Derived Endozoic Fungus Talaromyces scorteus AS-242[J]. JOURNAL OF NATURAL PRODUCTS,2020,83(8):2528-2536.
APA	Meng, Ling-Hong,Li, Xiao-Ming,Zhang, Fan-Zhong,Wang, Ya-Nan,&Wang, Bin-Gui.(2020).Talascortenes A-G, Highly Oxygenated Diterpenoid Acids from the Sea-Anemone-Derived Endozoic Fungus Talaromyces scorteus AS-242.JOURNAL OF NATURAL PRODUCTS,83(8),2528-2536.
MLA	Meng, Ling-Hong,et al."Talascortenes A-G, Highly Oxygenated Diterpenoid Acids from the Sea-Anemone-Derived Endozoic Fungus Talaromyces scorteus AS-242".JOURNAL OF NATURAL PRODUCTS 83.8(2020):2528-2536.

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