Genomic Architecture of Rapid Parallel Adaptation to Fresh Water in a Wild Fish

doi:10.1093/molbev/msaa290

	Genomic Architecture of Rapid Parallel Adaptation to Fresh Water in a Wild Fish
	Zong, Shao-Bing 1,4; Li, Yu-Long1,2,3 ; Liu, Jin-Xian 1,2,3
	2021-04-01
发表期刊	MOLECULAR BIOLOGY AND EVOLUTION
ISSN	0737-4038
卷号	38 期号:4 页码:1317-1329
通讯作者	Liu, Jin-Xian(jinxianliu@gmail.com)
摘要	Rapid adaptation to novel environments may drive changes in genomic regions through natural selection. However, the genetic architecture underlying these adaptive changes is still poorly understood. Using population genomic approaches, we investigated the genomic architecture that underlies rapid parallel adaptation of Coilia nasus to fresh water by comparing four freshwater-resident populations with their ancestral anadromous population. Linkage disequilibrium network analysis and population genetic analyses revealed two putative large chromosome inversions on LG6 and LG22, which were enriched for outlier loci and exhibited parallel association with freshwater adaptation. Drastic frequency shifts and elevated genetic differentiation were observed for the two chromosome inversions among populations, suggesting that both inversions would undergo divergent selection between anadromous and resident ecotypes. Enrichment analysis of genes within chromosome inversions showed significant enrichment of genes involved in metabolic process, immunoregulation, growth, maturation, osmoregulation, and so forth, which probably underlay differences in morphology, physiology and behavior between the anadromous and freshwater-resident forms. The availability of beneficial standing genetic variation, large optimum shift between marine and freshwater habitats, and high efficiency of selection with large population size could lead to the observed rapid parallel adaptive genomic change. We propose that chromosomal inversions might have played an important role during the evolution of rapid parallel ecological divergence in the face of environmental heterogeneity in C. nasus. Our study provides insights into the genomic basis of rapid adaptation of complex traits in novel habitats and highlights the importance of structural genomic variants in analyses of ecological adaptation.
关键词	parallel evolution local adaptation chromosome inversion complex traits standing genetic variation
DOI	10.1093/molbev/msaa290
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[41676137] ; National Natural Science Foundation of China[41906080]
WOS研究方向	Biochemistry & Molecular Biology ; Evolutionary Biology ; Genetics & Heredity
WOS类目	Biochemistry & Molecular Biology ; Evolutionary Biology ; Genetics & Heredity
WOS记录号	WOS:000648996500008
出版者	OXFORD UNIV PRESS
引用统计	被引频次：16[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/176778
专题	海洋生态与环境科学重点实验室
通讯作者	Liu, Jin-Xian
作者单位	1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Ecol & Environm Sci, Qingdao, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao, Peoples R China 4.Univ Chinese Acad Sci, Beijing, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所; 中国科学院海洋大科学研究中心
推荐引用方式 GB/T 7714	Zong, Shao-Bing,Li, Yu-Long,Liu, Jin-Xian. Genomic Architecture of Rapid Parallel Adaptation to Fresh Water in a Wild Fish[J]. MOLECULAR BIOLOGY AND EVOLUTION,2021,38(4):1317-1329.
APA	Zong, Shao-Bing,Li, Yu-Long,&Liu, Jin-Xian.(2021).Genomic Architecture of Rapid Parallel Adaptation to Fresh Water in a Wild Fish.MOLECULAR BIOLOGY AND EVOLUTION,38(4),1317-1329.
MLA	Zong, Shao-Bing,et al."Genomic Architecture of Rapid Parallel Adaptation to Fresh Water in a Wild Fish".MOLECULAR BIOLOGY AND EVOLUTION 38.4(2021):1317-1329.

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