Selective ATP Detection via Activation of MoS2-Based Artificial Nanozymes Inhibited by ZIF-90 Nanoparticles

doi:10.1021/acsanm.1c01986

	Selective ATP Detection via Activation of MoS2-Based Artificial Nanozymes Inhibited by ZIF-90 Nanoparticles
	Wang, Yingwen 1,2,3; Zhang, Dun 1,2,3; Zeng, Yan1,3 ; Qi, Peng1,2,3
	2021-11-26
发表期刊	ACS APPLIED NANO MATERIALS
卷号	4 期号:11 页码:11545-11553
通讯作者	Zhang, Dun(zhangdun@qdio.ac.cn) ; Qi, Peng(qipeng@qdio.ac.cn)
摘要	In this paper, we presented an ATP detection platform based on the selective activation of an artificial nanozyme inhibited by ZIF-90 nanoparticles. For the first time, we found and reported the inhibitory effect of ZIF-90 nanoparticles on the MoS2 nanozyme, and this property was integrated with its ATP-responsive ability to develop an ATP detection biosensor. The presence of ATP triggers the decomposition of ZIF-90, thus eliminating the inhibition ability and recovering the catalytic ability of the MoS2 nanozyme. By measuring the catalytic activity in the H2O2 -TMB reaction system with optical and electrochemical methods, the ATP detection performance was evaluated systematically. The proposed detection method exhibited excellent sensitivity and selectivity, and the optical and electrochemical modes satisfied the requirements of different application circumstances. In addition, taking advantage of the mild and rapid bacterial disintegration properties of antibiotic peptide-modified magnetic nanoparticles (M-AMPs), using the proposed platform based on selective activation of ZIF-90 nanoparticles inhibited the MoS2 nanozyme, discriminative ATP detection was performed. This work confirms that the inhibitory effect of ZIF-90 nanoparticles on the MoS2 artificial nanozyme provides an idea for developing biosensing systems based on enzyme inhibition and, more importantly, holds great potential for expanding the application of ZIF-90 nanoparticles in analytical fields.
关键词	ZIF-90 nanoparticles MoS2 nanozyme inhibitory effect discriminative ATP detection optical and electrochemical modes
DOI	10.1021/acsanm.1c01986
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[41876101] ; National Natural Science Foundation of China[41906037] ; Nantong Scientific Plan Foundation[JC2021054] ; Nantong Scientific Plan Foundation[2020NT04]
WOS研究方向	Science & Technology - Other Topics ; Materials Science
WOS类目	Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary
WOS记录号	WOS:000752894100015
出版者	AMER CHEMICAL SOC
引用统计	被引频次：11[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/177994
专题	海洋环境腐蚀与生物污损重点实验室
通讯作者	Zhang, Dun; Qi, Peng
作者单位	1.Chinese Acad Sci, Key Lab Marine Environm Corros & Biofouling, Inst Oceanol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 3.Pilot Natl Lab Marine Sci & Technol Qingdao, Open Studio Marine Corros & Protect, Qingdao 266237, Shandong, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Wang, Yingwen,Zhang, Dun,Zeng, Yan,et al. Selective ATP Detection via Activation of MoS2-Based Artificial Nanozymes Inhibited by ZIF-90 Nanoparticles[J]. ACS APPLIED NANO MATERIALS,2021,4(11):11545-11553.
APA	Wang, Yingwen,Zhang, Dun,Zeng, Yan,&Qi, Peng.(2021).Selective ATP Detection via Activation of MoS2-Based Artificial Nanozymes Inhibited by ZIF-90 Nanoparticles.ACS APPLIED NANO MATERIALS,4(11),11545-11553.
MLA	Wang, Yingwen,et al."Selective ATP Detection via Activation of MoS2-Based Artificial Nanozymes Inhibited by ZIF-90 Nanoparticles".ACS APPLIED NANO MATERIALS 4.11(2021):11545-11553.