The Cell Wall Polysaccharides Biosynthesis in Seaweeds: A Molecular Perspective

doi:10.3389/fpls.2022.902823

IOCAS-IR > 实验海洋生物学重点实验室

	The Cell Wall Polysaccharides Biosynthesis in Seaweeds: A Molecular Perspective
	Shao, Zhanru 1,2; Duan, Delin 1,2,3
	2022-05-10
发表期刊	FRONTIERS IN PLANT SCIENCE
ISSN	1664-462X
卷号	13 页码:7
通讯作者	Duan, Delin(dlduan@qdio.ac.cn)
摘要	Cell wall polysaccharides (CWPS) of seaweeds play crucial roles in mechanical shear resistance, cell-cell adhesion and the interactions with changeable marine environments. They have diverse applications in food, cosmetics, agriculture, pharmaceuticals and therapeutics. The recent boost of multi-omics sequence analysis has rapidly progressed the mining of presumed genes encoding enzymes involved in CWPS biosynthesis pathways. In this review, we summarize the biosynthetic pathways of alginate, fucoidan, agar, carrageenan and ulvan in seaweeds referred to the literatures on published genomes and biochemical characterization of encoded enzymes. Some transcriptomic data were briefly reported to discuss the correlation between gene expression levels and CWPS contents. Mannuronan C-5 epimerase (MC5E) and carbohydrate sulfotransferase (CST) are crucial enzymes for alginate and sulfated CWPS, respectively. Nonetheless, most CWPS-relevant genes were merely investigated by gene mining and phylogenetic analysis. We offer an integrative view of CWPS biosynthesis from a molecular perspective and discuss about the underlying regulation mechanism. However, a clear understanding of the relationship between chemical structure and bioactivities of CWPS is limited, and reverse genetic manipulation and effective gene editing tools need to be developed in future.
关键词	cell wall polysaccharide gene mining mannuronan C-5 epimerase carbohydrate sulfotransferase biosynthesis
DOI	10.3389/fpls.2022.902823
收录类别	SCI
语种	英语
资助项目	National Key R&D Program of China[2018YFD0900106] ; Youth Innovation Promotion Association CAS[2022205]
WOS研究方向	Plant Sciences
WOS类目	Plant Sciences
WOS记录号	WOS:000802268900001
出版者	FRONTIERS MEDIA SA
引用统计	被引频次：18[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/179342
专题	实验海洋生物学重点实验室
通讯作者	Duan, Delin
作者单位	1.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, CAS & Shandong Prov Key Lab Expt Marine Biol, Qingdao, Peoples R China 2.Lab Marine Biol & Biotechnol, Pilot Natl Lab Marine Sci & Technol, Qingdao, Peoples R China 3.Qingdao Bright Moon Seaweed Grp Co Ltd, State Key Lab Bioact Seaweed Subst, Qingdao, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Shao, Zhanru,Duan, Delin. The Cell Wall Polysaccharides Biosynthesis in Seaweeds: A Molecular Perspective[J]. FRONTIERS IN PLANT SCIENCE,2022,13:7.
APA	Shao, Zhanru,&Duan, Delin.(2022).The Cell Wall Polysaccharides Biosynthesis in Seaweeds: A Molecular Perspective.FRONTIERS IN PLANT SCIENCE,13,7.
MLA	Shao, Zhanru,et al."The Cell Wall Polysaccharides Biosynthesis in Seaweeds: A Molecular Perspective".FRONTIERS IN PLANT SCIENCE 13(2022):7.

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