Novel thorned Ag4V2O7 nanorods: Intrinsic oxidase-like catalytic activity for antibacterial application

doi:10.1016/j.inoche.2024.112839

	Novel thorned Ag4V2O7 nanorods: Intrinsic oxidase-like catalytic activity for antibacterial application
	Shen, Hengxia 1; Xiang, Zhenbo2,3
	2024-10-01
发表期刊	INORGANIC CHEMISTRY COMMUNICATIONS
ISSN	1387-7003
卷号	168 页码:9
通讯作者	Xiang, Zhenbo(xiangzhenbo1@126.com.com)
摘要	Enhancing the bactericidal properties of nanozymes and eliminating the need for H2O2 are crucial for biosafety and public hygiene. In this study, we introduce a novel thorned Ag4V2O7 nanorods for the first time, demonstrating their potential as oxidase-like and antibacterial agents. Due to their remarkable oxidase-like activity, Ag4V2O7 nanorods demonstrate potent bactericidal activity against both Escherichia coli, a representative Gramnegative bacterium, and Staphylococcus aureus, a prototypical Gram-positive bacterium, without the need for H2O2. The minimum inhibitory concentrations of Ag4V2O7 nanorods against Escherichia coli and Staphylococcus aureus are 0.78 and 1.56 mu g/mL, respectively, while their minimum bactericidal concentrations are also 1.56 and 3.12 mu g/mL. The bactericidal mechanism was investigated using electron paramagnetic resonance, radical trapping experiments and transmission electron microscopy analysis, which indicated that the Ag4V2O7 nanorods produce superoxide radicals to disrupt bacterial cell walls and membranes, leading to bacterial death. Notably, the nanorods maintained their antibacterial activity even after five bactericidal cycles, highlighting their stability and potential for practical applications in antimicrobial agents. Overall, our findings contribute to the advancement of medical science and environmental catalysis applications.
关键词	Ag 4 V 2 O 7 nanorods Nanozymes Oxidase-like Sterilization Sterilization mechanism
DOI	10.1016/j.inoche.2024.112839
收录类别	SCI
语种	英语
资助项目	Shandong Provincial Natural Science Foundation[ZR2020QB107]
WOS研究方向	Chemistry
WOS类目	Chemistry, Inorganic & Nuclear
WOS记录号	WOS:001269040600001
出版者	ELSEVIER
WOS关键词	NANOPARTICLES ; PERFORMANCE ; NANOZYMES
引用统计
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/186213
专题	海洋环境腐蚀与生物污损重点实验室
通讯作者	Xiang, Zhenbo
作者单位	1.Rizhao Polytech, Dept Marine Technol, Rizhao 276826, Shandong, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Key Lab Marine Environm Corros & Biofouling, Qingdao 266071, Shandong, Peoples R China 3.Rizhao Sci & Technol Innovat Serv Ctr, Rizhao 276800, Peoples R China
通讯作者单位	海洋环境腐蚀与生物污损重点实验室
推荐引用方式 GB/T 7714	Shen, Hengxia,Xiang, Zhenbo. Novel thorned Ag4V2O7 nanorods: Intrinsic oxidase-like catalytic activity for antibacterial application[J]. INORGANIC CHEMISTRY COMMUNICATIONS,2024,168:9.
APA	Shen, Hengxia,&Xiang, Zhenbo.(2024).Novel thorned Ag4V2O7 nanorods: Intrinsic oxidase-like catalytic activity for antibacterial application.INORGANIC CHEMISTRY COMMUNICATIONS,168,9.
MLA	Shen, Hengxia,et al."Novel thorned Ag4V2O7 nanorods: Intrinsic oxidase-like catalytic activity for antibacterial application".INORGANIC CHEMISTRY COMMUNICATIONS 168(2024):9.