Differential gene expression in the respiratory tree of the sea cucumber Apostichopus japonicus during aestivation

doi:10.1016/j.margen.2014.07.001

	Differential gene expression in the respiratory tree of the sea cucumber Apostichopus japonicus during aestivation
	Zhao, Ye1,2 ; Yang, Hongsheng1 ; Storey, Kenneth B.3; Chen, Muyan 4; Yang, HS (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China.
	2014-12-01
发表期刊	MARINE GENOMICS
卷号	18 页码:173-183
文章类型	Article
摘要	Sea cucumbers, Apostichopus japonicus, experience seasonally high water temperatures during the summer months and enter aestivation to survive. Aestivation is characterized by strong metabolic rate depression which is supported by a series of strategies including reorganizing metabolic processes, suppressing cell functions, enhancing cytoprotective mechanisms, and altered gene expression. The respiratory tree tissue of the sea cucumber is an excellent material for studying aestivation, undergoing obvious atrophy during aestivation. The present study analyzed the global gene expression profile of respiratory tree tissue of A. japonicus during aestivation by constructing and screening three libraries representing key stages of aestivation: non-aestivation (NA), deep-aestivation (DA), and arousal from aestivation (M) using RNA-seq. A total of 1240, 1184 and 303 differentially expressed genes (DEGs) were identified following the criteria of [log(2) ratiol >= 1 and FDR <= 0.001 in comparisons of DA vs. NA, AA vs. NA and DA vs. AA. A set of respiratory tree specific DEGs was identified the first time and, in addition, common DEGs that were responsive to aestivation in both respiratory tree and intestine were identified. Functional analysis of DEGs was further performed by GO enrichment analysis and respiratory tree specific GO terms were screened out and provide interesting hints for further studies of the molecular regulation of aestivation in A. japonicus. (c) 2014 Elsevier B.V. All rights reserved.
关键词	Apostichopus Japonicus Rna-seq Respiratory Tree Aestivation Differential Gene Expression
学科领域	Genetics & Heredity ; Marine & Freshwater Biology
DOI	10.1016/j.margen.2014.07.001
收录类别	SCI
语种	英语
WOS记录号	WOS:000347578600024
引用统计	被引频次：29[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/24002
专题	海洋生态与环境科学重点实验室
通讯作者	Yang, HS (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China.
作者单位	1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Carleton Univ, Inst Biochem, Ottawa, ON K1S 5B6, Canada 4.Ocean Univ China, Coll Fisheries, Qingdao 266003, Peoples R China
第一作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Zhao, Ye,Yang, Hongsheng,Storey, Kenneth B.,et al. Differential gene expression in the respiratory tree of the sea cucumber Apostichopus japonicus during aestivation[J]. MARINE GENOMICS,2014,18:173-183.
APA	Zhao, Ye,Yang, Hongsheng,Storey, Kenneth B.,Chen, Muyan,&Yang, HS .(2014).Differential gene expression in the respiratory tree of the sea cucumber Apostichopus japonicus during aestivation.MARINE GENOMICS,18,173-183.
MLA	Zhao, Ye,et al."Differential gene expression in the respiratory tree of the sea cucumber Apostichopus japonicus during aestivation".MARINE GENOMICS 18(2014):173-183.

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