Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
N-Formyllapatin A, a new N-formylspiroquinazoline derivative from the marine-derived fungus Penicillium adametzioides AS-53 | |
Liu, Yang1,2![]() ![]() ![]() | |
2014-12-01 | |
发表期刊 | PHYTOCHEMISTRY LETTERS
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卷号 | 10页码:145-148 |
文章类型 | Article |
摘要 | N-Formyllapatin A (1), a new spiroquinazoline derivative, and four known quinazoline metabolites, lapatins A (2) and B (3), prelapatin B (4), and glyantrypine (5), along with two known indolediketopiperazine derivatives, fumitremorgin B (6) and verruculogen (7), were characterized from Penicillium adametzioides AS-53, a fungus obtained from the fresh tissue of an unidentified marine sponge. The structure of compound 1 was established by detailed interpretation of NMR and MS data, and its absolute configuration was established by a single-crystal X-ray diffraction analysis. N-Formyllapatin A (1) represents the first N-formylspiroquinazoline secondary metabolite. Compounds 3 and 5-7 showed moderate inhibitory activity against aqua-pathogenic bacterial Vibrio harveyi. (C) 2014 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved. |
关键词 | Marine Sponge-derived Fungus Penicillium Adametzioides Secondary Metabolites Spiroquinazoline Derivative Antibacterial Activity |
学科领域 | Biochemistry & Molecular Biology ; Plant Sciences |
DOI | 10.1016/j.phytol.2014.08.018 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000347915800048 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.qdio.ac.cn/handle/337002/24133 |
专题 | 实验海洋生物学重点实验室 海洋生态与环境科学重点实验室 |
通讯作者 | Wang, BG (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China. |
作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
第一作者单位 | 实验海洋生物学重点实验室 |
推荐引用方式 GB/T 7714 | Liu, Yang,Li, Xiao-Ming,Meng, Ling-Hong,et al. N-Formyllapatin A, a new N-formylspiroquinazoline derivative from the marine-derived fungus Penicillium adametzioides AS-53[J]. PHYTOCHEMISTRY LETTERS,2014,10:145-148. |
APA | Liu, Yang,Li, Xiao-Ming,Meng, Ling-Hong,Wang, Bin-Gui,&Wang, BG .(2014).N-Formyllapatin A, a new N-formylspiroquinazoline derivative from the marine-derived fungus Penicillium adametzioides AS-53.PHYTOCHEMISTRY LETTERS,10,145-148. |
MLA | Liu, Yang,et al."N-Formyllapatin A, a new N-formylspiroquinazoline derivative from the marine-derived fungus Penicillium adametzioides AS-53".PHYTOCHEMISTRY LETTERS 10(2014):145-148. |
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