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Sulfated Polysaccharides Isolated from Cloned Grateloupia filicina and Their Anticoagulant Activity
Chen, Xiaolin1; Yang, Shengfeng2; Wang, Jinxia1; Song, Lin1; Xing, Ronge1; Liu, Song1; Yu, Huahua1; Li, Pengcheng1
2015
发表期刊Biomed Research International
文章类型Article
摘要Sulfated polysaccharides (GSP) were isolated from the cloned Grateloupia filicina which was cultured in Jiaozhou Bay, Qingdao, China. The yield of GSP was 15.75%. The total sugar and sulfate were 40.90 and 19.89%, respectively. And the average molecular weight was 11.7 KDa. The results of neutral sugar analysis showed that GSP was mainly sulfated polysaccharides of galactose. The experiments for activated partial thromboplastin time (APTT), prothrombin time (PT), and thrombin time (TT) anticoagulant assays in vitro indicated that GSP was a good potential anticoagulant. Therefore, this study supplied new thought for the cloned Grateloupia filicina exploitation of high-value products.
DOI10.1155/2015/612352
收录类别SCI
语种英语
WOS记录号WOS:000353244700001
引用统计
被引频次:15[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/25481
专题海洋生物技术研发中心
实验海洋生物学重点实验室
海洋环境工程技术研究发展中心
作者单位1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Shandong, Peoples R China
2.Qingdao Tumor Hosp, Qingdao 266042, Shandong, Peoples R China
第一作者单位中国科学院海洋研究所
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GB/T 7714
Chen, Xiaolin,Yang, Shengfeng,Wang, Jinxia,et al. Sulfated Polysaccharides Isolated from Cloned Grateloupia filicina and Their Anticoagulant Activity[J]. Biomed Research International,2015.
APA Chen, Xiaolin.,Yang, Shengfeng.,Wang, Jinxia.,Song, Lin.,Xing, Ronge.,...&Li, Pengcheng.(2015).Sulfated Polysaccharides Isolated from Cloned Grateloupia filicina and Their Anticoagulant Activity.Biomed Research International.
MLA Chen, Xiaolin,et al."Sulfated Polysaccharides Isolated from Cloned Grateloupia filicina and Their Anticoagulant Activity".Biomed Research International (2015).
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