Comparative molecular population genetics of phycoerythrin locus in Prochlorococcus

doi:10.1007/s10709-006-0010-9

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	Comparative molecular population genetics of phycoerythrin locus in Prochlorococcus
	Zhao, Fangqing ; Qin, Song
	2007-03-01
发表期刊	GENETICA
ISSN	0016-6707
卷号	129 期号:3 页码:291-299
文章类型	Article
摘要	As the only remainder type of phycobiliproteins in Prochlorococcus, the actual role of phycoerythrin still remains unknown. Previous studies revealed that two different forms of phycoerythrin gene were found in two ecotypes of Prochlorococcus that are specifically adapted to either high light (HL) or low light (LL) conditions. Here we analyze patterns of phycoerythrin nucleotide variation in the HL- and LL-Prochlorococcus populations. Our analyses reveal a significantly greater number of non-synonymous fixed substitutions in peB and peA than expected based on interspecific comparisons. This pattern of excess non-synonymous fixed substitutions is not seen in other five phycoerythrin-related genes (peZ/V/Y/T/S). Several neutrality statistical tests indicate an excess of rare frequency polymorphisms in the LL-Prochlorococcus data, but an excess of intermediate frequency polymorphisms in the HL-Prochlorococcus data. Distributions of the positively selected sites identified using the likelihood ratio test, when mapped onto the phycoerythrin tertiary structure, reveal that HL- and LL-phycoerythrin should be under different selective patterns. These findings may provide insights into the likely role of selection at the phycoerythrin locus and motivate further research to unveil the function of phycoerythrin in Prochlorococcus.; As the only remainder type of phycobiliproteins in Prochlorococcus, the actual role of phycoerythrin still remains unknown. Previous studies revealed that two different forms of phycoerythrin gene were found in two ecotypes of Prochlorococcus that are specifically adapted to either high light (HL) or low light (LL) conditions. Here we analyze patterns of phycoerythrin nucleotide variation in the HL- and LL-Prochlorococcus populations. Our analyses reveal a significantly greater number of non-synonymous fixed substitutions in peB and peA than expected based on interspecific comparisons. This pattern of excess non-synonymous fixed substitutions is not seen in other five phycoerythrin-related genes (peZ/V/Y/T/S). Several neutrality statistical tests indicate an excess of rare frequency polymorphisms in the LL-Prochlorococcus data, but an excess of intermediate frequency polymorphisms in the HL-Prochlorococcus data. Distributions of the positively selected sites identified using the likelihood ratio test, when mapped onto the phycoerythrin tertiary structure, reveal that HL- and LL-phycoerythrin should be under different selective patterns. These findings may provide insights into the likely role of selection at the phycoerythrin locus and motivate further research to unveil the function of phycoerythrin in Prochlorococcus.
关键词	Neutrality Statistical Test Phycoerythrin Population Genetics Positive Selection Prochlorococcus
学科领域	Genetics & Heredity
DOI	10.1007/s10709-006-0010-9
URL	查看原文
收录类别	SCI
语种	英语
WOS记录号	WOS:000244092100008
引用统计	被引频次：9[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/5750
专题	实验海洋生物学重点实验室
作者单位	1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Qingdao, Peoples R China
推荐引用方式 GB/T 7714	Zhao, Fangqing,Qin, Song. Comparative molecular population genetics of phycoerythrin locus in Prochlorococcus[J]. GENETICA,2007,129(3):291-299.
APA	Zhao, Fangqing,&Qin, Song.(2007).Comparative molecular population genetics of phycoerythrin locus in Prochlorococcus.GENETICA,129(3),291-299.
MLA	Zhao, Fangqing,et al."Comparative molecular population genetics of phycoerythrin locus in Prochlorococcus".GENETICA 129.3(2007):291-299.

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