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Small Molecule SHP2 Inhibitor LXQ-217 affects Lung Cancer Cell Proliferation in Vitro and in Vivo 期刊论文
CHEMISTRY & BIODIVERSITY, 2024, 页码: 11
作者:  Sun, Hao;  Bai, Xiaoyi;  Zhang, Yiting;  Gao, Yanan;  Dai, Jiajia;  Xing, Pan;  Zhu, Jiqiang;  Liu, Ruihua;  Wang, Zemin;  Li, Xiangqian
收藏  |  浏览/下载：12/0  |  提交时间：2024/06/04
Anti-tumor  SHP2  Orthosteric inhibitor  Apoptosis  Bromophenol  
Fucoxanthin Alleviates Dextran Sulfate Sodium-Induced Colitis and Gut Microbiota Dysbiosis in Mice 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2024, 卷号: 72, 期号: 8, 页码: 4142-4154
作者:  Yang, Yu-Hong;  Chen, Chen;  Zheng, Yan;  Wu, Zi-Jian;  Zhou, Meng-Qing;  Liu, Xiao-Yong;  Miyashita, Kazuo;  Duan, De-Lin;  Du, Lei
收藏  |  浏览/下载：57/0  |  提交时间：2024/04/07
fucoxanthin  colitis  intestinal barrier function  anti-inflammation  antioxidation  gut microbiota  
JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia;  Liu, Ming
收藏  |  浏览/下载：39/0  |  提交时间：2024/04/07
Acquired resistance  Cancer  NSCLC  JC-010a  SHP2  
Comparative chromatin dynamics reveal differential thermal tolerance mechanisms between two congeneric oyster species 期刊论文
AQUACULTURE, 2024, 卷号: 579, 页码: 16
作者:  Wang, Chaogang;  Jiang, Zhuxiang;  Du, Mingyang;  Li, Qingyuan;  Cong, Rihao;  Wang, Wei;  Zhang, Guofan;  Li, Li
收藏  |  浏览/下载：37/0  |  提交时间：2024/04/07
Crassostrea gigas  Crassostrea angulata  ATAC-seq  RNA-Seq  Thermal tolerance  
Transcriptomic analysis reveals the immune response mechanisms of sea cucumber Apostichopus japonicus under noise stress from offshore wind turbine 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2024, 卷号: 906, 页码: 11
作者:  Cheng, Xiaochen;  Zhang, Libin;  Gao, Zhaoming;  Li, Kehan;  Xu, Jialei;  Liu, Weijian;  Ru, Xiaoshang
收藏  |  浏览/下载：40/0  |  提交时间：2024/04/07
Offshore wind power  Underwater noise  Sea cucumber  Invertebrate  Transcriptome  Immune response  
Chromosome-level genome assembly of the deep-sea snail Phymorhynchus buccinoides provides insights into the adaptation to the cold seep habitat 期刊论文
BMC GENOMICS, 2023, 卷号: 24, 期号: 1, 页码: 16
作者:  Liu, Zhaoqun;  Huang, Yuting;  Chen, Hao;  Liu, Chang;  Wang, Minxiao;  Bian, Chao;  Wang, Lingling;  Song, Linsheng
Adobe PDF(5637Kb)  |  收藏  |  浏览/下载：61/0  |  提交时间：2024/04/07
Cold seep  Phymorhynchus buccinoides  Chromosome-level genome  Glutamate regulation  Olfactory/chemosensory  H2S detoxification  
Penaeid Shrimp Chromosome Studies Entering the Post-Genomic Era 期刊论文
GENES, 2023, 卷号: 14, 期号: 11, 页码: 17
作者:  Zhang, Xiaojun;  Xiang, Jianhai;  Yuan, Jianbo;  Li, Fuhua
Adobe PDF(4084Kb)  |  收藏  |  浏览/下载：51/0  |  提交时间：2024/04/07
Litopenaeus vannamei  cytogenetics  genome  Hi-C  structure and function  
Genome-wide mapping of regulatory variants for temperature- and salinity-adaptive genes reveals genetic basis of genotype-by-environment interaction in Crassostrea ariakensis 期刊论文
ENVIRONMENTAL RESEARCH, 2023, 卷号: 236, 页码: 10
作者:  Zhang, Kexin;  Yang, Qi;  Du, Mingyang;  Zhang, Ziyan;  Wang, Wei;  Zhang, Guofan;  Li, Ao;  Li, Li
Adobe PDF(4626Kb)  |  收藏  |  浏览/下载：144/0  |  提交时间：2023/12/13
Temperature and salinity  Adaptation  Genotype-by-environment interaction  Gene expression  Cis-andtrans-eQTL  Crassostrea ariakensis  
Synergistic modulation of neuroendocrine-inflammation pathway by microRNAs facilitates intertidal adaptation of molluscs 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2023, 卷号: 142, 页码: 10
作者:  Chen, Hao;  Wang, Lin;  Wang, Lingling;  Zhang, Huan;  Wang, Hao;  Song, Linsheng
Adobe PDF(6028Kb)  |  收藏  |  浏览/下载：29/0  |  提交时间：2024/04/07
Inflammation response  Calmodulin  Nitrite oxide  Tumor necrosis factor  miRNAs  Aerial exposure  
Metabolomic insights into neurological effects of BDE-47 exposure in the sea cucumber Apostichopus japonicus 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2023, 卷号: 266, 页码: 11
作者:  Ding, Kui;  Xu, Qinzeng;  Zhang, Xuelei;  Liu, Shilin
Adobe PDF(3947Kb)  |  收藏  |  浏览/下载：14/0  |  提交时间：2024/04/07
Apostichopus japonicus  BDE-47  Nervous system  UPLC-Triple-TOF-MS  Metabolite  Neurotoxicity