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Small Molecule SHP2 Inhibitor LXQ-217 affects Lung Cancer Cell Proliferation in Vitro and in Vivo 期刊论文
CHEMISTRY & BIODIVERSITY, 2024, 页码: 11
作者:  Sun, Hao;  Bai, Xiaoyi;  Zhang, Yiting;  Gao, Yanan;  Dai, Jiajia;  Xing, Pan;  Zhu, Jiqiang;  Liu, Ruihua;  Wang, Zemin;  Li, Xiangqian
收藏  |  浏览/下载:12/0  |  提交时间:2024/06/04
Anti-tumor  SHP2  Orthosteric inhibitor  Apoptosis  Bromophenol  
JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia;  Liu, Ming
收藏  |  浏览/下载:39/0  |  提交时间:2024/04/07
Acquired resistance  Cancer  NSCLC  JC-010a  SHP2  
Distribution patterns of six metals and their influencing factors in M4 seamount seawater of the Western Pacific 期刊论文
MARINE POLLUTION BULLETIN, 2023, 卷号: 196, 页码: 9
作者:  Ma, Jun;  Li, Xuegang;  Song, Jinming;  Wen, Lilian;  Liang, Xianmeng;  Xu, Kuidong;  Dai, Jiajia
Adobe PDF(6075Kb)  |  收藏  |  浏览/下载:40/0  |  提交时间:2024/04/07
Seamount area  Metals  Western Pacific  Distribution pattern  Controlling factors  
The effects of seawater thermodynamic parameters on the oxygen minimum zone (OMZ) in the tropical western Pacific Ocean 期刊论文
MARINE POLLUTION BULLETIN, 2023, 卷号: 187, 页码: 12
作者:  Ma, Jun;  Li, Xuegang;  Song, Jinming;  Wen, Lilian;  Wang, Qidong;  Xu, Kuidong;  Dai, Jiajia;  Zhong, Guorong
收藏  |  浏览/下载:170/0  |  提交时间:2023/12/13
Oxygen minimum zone  Tropical western Pacific Ocean  Temperature  Salinity  Density  
Relationship and stratification of multiple marine ecological indicators: A case study in the M2 seamount area of the Western Pacific Ocean 期刊论文
ECOLOGICAL INDICATORS, 2023, 卷号: 146, 页码: 9
作者:  Ma, Jun;  Li, Xuegang;  Song, Jinming;  Wang, Qidong;  Wen, Lilian;  Xu, Kuidong;  Zhong, Guorong;  Dai, Jiajia;  Xing, Jianwei;  Tian, Detong
收藏  |  浏览/下载:232/0  |  提交时间:2023/11/16
Seawater stratification  Seamount  Western Pacific Ocean  Ecological effects  
The Fluoro-Thiazolylhydrazone Compound TSC-3C Inhibits Triple Negative Breast Cancer (TNBC) Cell Line Activity by Promoting Apoptosis, Regulating the MAPK Pathway and Inducing Mitochondrial Dysfunction 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 3, 页码: 15
作者:  Zhang, Jiajia;  Dai, Jiajia;  Zheng, Qingxuan;  Guo, Shuju;  Yu, Yanyan;  Hu, Wenpeng;  Gao, Yanan;  Shi, Dayong
Adobe PDF(2858Kb)  |  收藏  |  浏览/下载:203/0  |  提交时间:2020/09/23
triple negative breast cancer  MDA-MB-231 cells  fluoro-thiazolylhydrazone  MAPK pathway  phosphorylated p44/42 MAPK (ERK1/2)  phosphorylated c-Jun N-terminal kinase (p-JNK)  apoptosis