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Low molecular weight fucoidan LF2 improves the immunosuppressive tumor microenvironment and enhances the anti-pancreatic cancer activity of oxaliplatin 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2024, 卷号: 173, 页码: 10
作者:  Deng, Zhenzhen;  Qishan, Suo;  Zhang, Quanbin;  Wang, Jing;  Yue, Yang;  Geng, Lihua;  Wu, Ning
收藏  |  浏览/下载：61/0  |  提交时间：2024/06/04
Fucoidan  Tumor microenvironment  Macrophages  Oxaliplatin  
Pharmacokinetics of fucoidan and low molecular weight fucoidan from Saccharina japonica after oral administration to mice 期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2023, 页码: 10
作者:  Tan, Jiaojiao;  Song, Yimin;  Wang, Jing;  Wu, Ning;  Yue, Yang;  Zhang, Quanbin
收藏  |  浏览/下载：52/0  |  提交时间：2023/12/13
fucoidan  low molecular weight fucoidan  pharmacokinetics  bioavailability  tissue distribution  
Fucoidan, as an immunostimulator promotes M1 macrophage differentiation and enhances the chemotherapeutic sensitivity of capecitabine in colon cancer 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, 卷号: 222, 页码: 562-572
作者:  Deng, Zhenzhen;  Wu, Ning;  Suo, Qishan;  Wang, Jing;  Yue, Yang;  Geng, Lihua;  Zhang, Quanbin
Adobe PDF(8782Kb)  |  收藏  |  浏览/下载：230/0  |  提交时间：2023/01/04
Capecitabine  Tumor microenvironment  Macrophages  TLR4  Fucoidan  
The Involvement of the Mammalian Target of Rapamycin, Protein Tyrosine Phosphatase 1b and Dipeptidase 4 Signaling Pathways in Cancer and Diabetes: A Narrative Review 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 7, 页码: 803-815
作者:  Zhang, Jiajia;  Wu, Ning;  Shi, Dayong
Adobe PDF(1363Kb)  |  收藏  |  浏览/下载：387/0  |  提交时间：2021/05/11
Signaling pathway  mammalian target of rapamycin  protein tyrosine phosphatase 1b  dipeptidase 4  cancer  diabetes  pharmacology  target compounds  
An UHPLC-TOF-MS method for quantifying novel brominated anticancer compound bromophenol-thiosemicarbazone hybrid and its application to in vivo pharmacokinetic study 期刊论文
JOURNAL OF ANALYTICAL SCIENCE AND TECHNOLOGY, 2020, 卷号: 11, 期号: 1, 页码: 7
作者:  Li, Xiuxue;  Wang, Lijun;  Jia, Xiaoling;  Guo, Chuanlong;  Li, Chao;  Zhang, Jiajia;  Shi, Dayong
Adobe PDF(579Kb)  |  收藏  |  浏览/下载：242/0  |  提交时间：2020/09/23
Novel compound  Quantitation  UHPLC-TOF-MS  Pharmacokinetics  
The Fluoro-Thiazolylhydrazone Compound TSC-3C Inhibits Triple Negative Breast Cancer (TNBC) Cell Line Activity by Promoting Apoptosis, Regulating the MAPK Pathway and Inducing Mitochondrial Dysfunction 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 3, 页码: 15
作者:  Zhang, Jiajia;  Dai, Jiajia;  Zheng, Qingxuan;  Guo, Shuju;  Yu, Yanyan;  Hu, Wenpeng;  Gao, Yanan;  Shi, Dayong
Adobe PDF(2858Kb)  |  收藏  |  浏览/下载：239/0  |  提交时间：2020/09/23
triple negative breast cancer  MDA-MB-231 cells  fluoro-thiazolylhydrazone  MAPK pathway  phosphorylated p44/42 MAPK (ERK1/2)  phosphorylated c-Jun N-terminal kinase (p-JNK)  apoptosis  
Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 15
作者:  Xu, Qi;  Wu, Ning;  Li, Xiangqian;  Guo, Chuanlong;  Li, Chao;  Jiang, Bo;  Wang, Huaizhi;  Shi, Dayong
Adobe PDF(3632Kb)  |  收藏  |  浏览/下载：391/0  |  提交时间：2020/03/20