Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
Preparation, characterization, and antifungal evaluation of a new type of aminourea chitooligosaccharide derivatives | |
Zhu Jun1,3; Liu Song1,2; Qin Yukun1,2; Xing Rong'e1,2; Yu Huahua1,2; Chen Xiaolin1,2; Li Pengcheng1,2 | |
2019-12-23 | |
发表期刊 | JOURNAL OF OCEANOLOGY AND LIMNOLOGY |
ISSN | 2096-5508 |
页码 | 10 |
摘要 | Phytopathogenic fungi cause heavy negative impact on the agricultural economy, but most existing fungicides are toxic and pose a threat to both human health and environments. A green and efficient fungicide is urgently needed. Chitooligosaccharides (COSs), the degradation products of natural polysaccharide chitosan, are nontoxic and biodegradable antifungal substances. In this study, a novel type of aminourea chitooligosaccharide derivatives (AUCOS) was synthesized by successively grafting a hydrazine group and an amine-carbonyl group onto a chitooligosaccharide backbone to enhance the antifungal capability of COSs. The structures of the target compounds were identified by FTIR, (1) H NMR, and (13) C NMR, and the degree of substitution of each product was calculated from the results of the elemental analysis. The antifungal activities of the prepared chitooligosaccharide derivatives against Fusarium solani Verticillium albo- atrum and Phytophthora capsici were tested in vitro. The AUCOSs had better inhibitory efficiencies against the three plant pathogen fungi than that of chitooligosaccharide, of which aminourea chitooligosaccharide 2 (AUCOS2) was the most promising antifungal compound, whose highest inhibition rates were 60.12%, 82.95%, and 85.23% against F solani V albo- atrum and P capsici, respectively. The synthesized derivatives have good application prospects in crop protection and deserve further research. |
关键词 | chitooligosaccharide (COS) aminourea characterization antifungal |
DOI | 10.1007/s00343-019-9099-4 |
收录类别 | SCI |
语种 | 英语 |
资助项目 | Shandong Province Key Research and Development Project[2018GHY115008] ; Qingdao Science and Technology Project[17-3-3-60-nsh] ; Qingdao Science and Technology Project[17-3-3-60-nsh] ; Shandong Province Key Research and Development Project[2018GHY115008] |
WOS研究方向 | Marine & Freshwater Biology ; Oceanography |
WOS类目 | Limnology ; Oceanography |
WOS记录号 | WOS:000504123300002 |
出版者 | SCIENCE PRESS |
引用统计 | |
文献类型 | 期刊论文 |
版本 | 出版稿 |
条目标识符 | http://ir.qdio.ac.cn/handle/337002/164191 |
专题 | 实验海洋生物学重点实验室 |
通讯作者 | Liu Song; Li Pengcheng |
作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Pilot Natl Lab Marine Sci & Technol Qingdao, Lab Marine Drugs & Bioprod, Qingdao 266237, Shandong, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
第一作者单位 | 中国科学院海洋研究所 |
通讯作者单位 | 中国科学院海洋研究所 |
推荐引用方式 GB/T 7714 | Zhu Jun,Liu Song,Qin Yukun,et al. Preparation, characterization, and antifungal evaluation of a new type of aminourea chitooligosaccharide derivatives[J]. JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2019:10. |
APA | Zhu Jun.,Liu Song.,Qin Yukun.,Xing Rong'e.,Yu Huahua.,...&Li Pengcheng.(2019).Preparation, characterization, and antifungal evaluation of a new type of aminourea chitooligosaccharide derivatives.JOURNAL OF OCEANOLOGY AND LIMNOLOGY,10. |
MLA | Zhu Jun,et al."Preparation, characterization, and antifungal evaluation of a new type of aminourea chitooligosaccharide derivatives".JOURNAL OF OCEANOLOGY AND LIMNOLOGY (2019):10. |
条目包含的文件 | ||||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
Preparation, charact(901KB) | 期刊论文 | 作者接受稿 | 限制开放 | CC BY-NC-SA | 浏览 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论