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Small Molecule SHP2 Inhibitor LXQ-217 affects Lung Cancer Cell Proliferation in Vitro and in Vivo 期刊论文
CHEMISTRY & BIODIVERSITY, 2024, 页码: 11
作者:  Sun, Hao;  Bai, Xiaoyi;  Zhang, Yiting;  Gao, Yanan;  Dai, Jiajia;  Xing, Pan;  Zhu, Jiqiang;  Liu, Ruihua;  Wang, Zemin;  Li, Xiangqian
收藏  |  浏览/下载：23/0  |  提交时间：2024/06/04
Anti-tumor  SHP2  Orthosteric inhibitor  Apoptosis  Bromophenol  
JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia;  Liu, Ming
收藏  |  浏览/下载：55/0  |  提交时间：2024/04/07
Acquired resistance  Cancer  NSCLC  JC-010a  SHP2  
Megalocytivirus Induces Complicated Fish Immune Response at Multiple RNA Levels Involving mRNA, miRNA, and circRNA 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 6, 页码: 20
作者:  Wu, Qian;  Ning, Xianhui;  Sun, Li
Adobe PDF(2356Kb)  |  收藏  |  浏览/下载：289/0  |  提交时间：2021/06/04
Paralichthys olivaceus  megalocytivirus  miRNA  ceRNA  immune response  
Microbial communities present on mooring chain steels with different copper contents and corrosion rates 期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2020, 卷号: 38, 期号: 2, 页码: 378-394
作者:  Wu, Jiajia;  Gao, Jieyan;  Zhang, Dun;  Tan, Faqi;  Yin, Jiang;  Wang, Yu;  Sun, Yan;  Li, Ee
Adobe PDF(3691Kb)  |  收藏  |  浏览/下载：229/0  |  提交时间：2020/09/24
marine corrosion  microbially influenced corrosion  microbial community  mooring chain steel  copper introduction  
Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 134, 页码: 24-33
作者:  Zhang, Renshuai;  Yu, Rilei;  Xu, Qi;  Li, Xiangqian;  Luo, Jiao;  Jiang, Bo;  Wang, Lijun;  Guo, Shuju;  Wu, Ning;  Shi, Dayong
Adobe PDF(3126Kb)  |  收藏  |  浏览/下载：297/0  |  提交时间：2017/07/10
Ptp1b  Bromophenol  Saccharide  Selectivity  Permeability  
A novel siglec (CgSiglec-1) from the Pacific oyster (Crassostrea gigas) with broad recognition spectrum and inhibitory activity to apoptosis, phagocytosis and cytokine release 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2016, 卷号: 61, 页码: 136-144
作者:  Liu, Conghui;  Jiang, Shuai;  Wang, Mengqiang;  Wang, Lingling;  Chen, Hao;  Xu, Jiachao;  Lv, Zhao;  Song, Linsheng
Adobe PDF(2034Kb)  |  收藏  |  浏览/下载：285/1  |  提交时间：2016/08/24
Sialic Acid Binding Immunoglobulin-type Lectins  Innate Immune Response  Recognition Spectrum  Cascading Inhibitory  Phagocytosis  
Comparative Transcriptomic Characterization of the Early Development in Pacific White Shrimp Litopenaeus vannamei 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 9, 页码: e106201
作者:  Wei, Jiankai;  Zhang, Xiaojun;  Yu, Yang;  Huang, Hao;  Li, Fuhua;  Xiang, Jianhai;  Xiang, JH (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao, Peoples R China.
Adobe PDF(1384Kb)  |  收藏  |  浏览/下载：233/0  |  提交时间：2015/06/11
Transcriptome Analysis and Discovery of Genes Involved in Immune Pathways from Hepatopancreas of Microbial Challenged Mitten Crab Eriocheir sinensis 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 7, 页码: e68233
作者:  Li, Xihong;  Cui, Zhaoxia;  Liu, Yuan;  Song, Chengwen;  Shi, Guohui;  Cui, ZX
Adobe PDF(1614Kb)  |  收藏  |  浏览/下载：219/0  |  提交时间：2014/07/17
Bromophenols as inhibitors of protein tyrosine phosphatase 1B with antidiabetic properties 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 8, 页码: 2827-2832
作者:  Shi, Dayong;  Li, Jing;  Jiang, Bo;  Guo, Shuju;  Su, Hua;  Wang, Tao;  Shi, DY (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China.
Adobe PDF(448Kb)  |  收藏  |  浏览/下载：367/1  |  提交时间：2013/09/24
Bromophenol Derivatives  Protein Tyrosine Phosphatase 1b  Diarylmethane  Antidiabetic Activities